Anti-exercise Fatigue Mechanism of Action

Exercise fatigue is a physiological phenomenon that occurs when the human body's mental and physical activities reach a certain stage, which is manifested by the inability of the body's physiological processes to continue their functions at a specific level and/or to maintain the intended exercise intensity. How to prevent the occurrence of exercise fatigue and how to recover from exercise fatigue is a major concern nowadays. Plant extracts have anti-fatigue activity, which is of great theoretical value and practical significance for the prevention and elimination of exercise fatigue. Lifeasible is oriented to the mechanism of action of plant extracts in anti-fatigue and will help you to study the mechanism of action of polyphenols, alkaloids, saponins, polysaccharides, etc., in the human body. To provide technical support for your research and development of new anti-exercise fatigue functional products and selection of green, effective, and safe food-borne active ingredients.

Our Services for Anti-exercise Fatigue Mechanism Study

Exercise fatigue is a complex physiological process, and the two main methods for evaluating fatigue are the endurance test and the detection of biochemical changes. We can comprehensively and systematically evaluate the anti-exercise fatigue activity of plant extracts through the exercise endurance test and the examination of anti-exercise fatigue biochemical indexes, including hepatic glycogen, blood urea nitrogen (BUN), and whole blood lactic acid (LD) values in mice. The indicators we selected can satisfy the characteristics of sensitive detection method, simple and easy operation, and the results can objectively reflect the fatigue level of the organism.

• Exercise endurance test.
  We mostly use the swimming test, and to shorten the swimming time, we usually use the method of weight-bearing swimming. If the swimming time of the subject group is longer than that of the control group, and the difference is significant, it can be judged that the subject can prolong the swimming time of mice.
• Liver glycogen assay.
  Livers were removed by necropsy immediately after swimming, and the content of liver glycogen was determined by the classical anthrone method.
• BUN assay.
  We took blood from the eyeballs and measured the BUN content by the diacetyl-oxime method.
• LD determination.
  Blood was taken in a quiet state and then at intervals immediately after weight-bearing swimming in mice and measured using a lactate meter.

Due to the number of factors involved, Lifeasible uses a control group for each test for each specimen, rather than comparing the results to normal values or the results of a control group in a particular test. We do not make conclusions based on the results of a single test but rather provide comprehensive, objective results to determine whether the test specimen has an anti-fatigue effect.

Please feel free to contact us to submit your requirements, and we will provide you with the optimal solution.

※ For research or industrial raw materials, not for personal medical use!